Why Prescribe Highly Purified Factor VIII and IX Concentrates?

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PREPARATION OF HIGHLY PURIFIED SOLVENTDETERGENT COA GULATION FACTOR VII AND FACTOR IX CONCENTRATES FROM PROTHROMBIN COMPLEX (PPSB)

In this study, anion-exchange chromatography was used to purify factor VII and factor IX from prothrombin complex (PPSB), which contains coagulation factors II, VII, IX and X. For this purpose, DEAE-Sepharose CL-6B gel , Pharmacia column XK-26 , high flow rate and two stepwise gradients with phosphate citrate buffer were used. The yield of the two lyophylized products, factor VII and factor...

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6 Factor VIII Concentrates, Factor VIII/von Willebrand Factor Concentrates, Factor IX Concentrates, Activated Prothrombin Complex Concentrates.

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preparation of highly purified solventdetergent coa gulation factor vii and factor ix concentrates from prothrombin complex (ppsb)

in this study, anion-exchange chromatography was used to purify factor vii and factor ix from prothrombin complex (ppsb), which contains coagulation factors ii, vii, ix and x. for this purpose, deae-sepharose cl-6b gel , pharmacia column xk-26 , high flow rate and two stepwise gradients with phosphate citrate buffer were used. the yield of the two lyophylized products, factor vii and factor ix ...

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Recommendations on the potency labelling of factor VIII and factor IX concentrates.

Project members: AR Hubbard, J Dodt, T Lee, K Mertens, R Seitz, A Srivastava, M Weinstein National Institute for Biological Standards and Control, Potters Bar, UK; Paul-EhrlichInstitut, Langen, Germany; Center for Biologics Evaluation & Research/Food and Drug Administration, Rockville MD, USA; Sanquin Blood Supply Foundation, Amsterdam, The Netherlands; Christian Medical College, Vellore, India.

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ژورنال

عنوان ژورنال: Vox Sanguinis

سال: 1996

ISSN: 0042-9007,1423-0410

DOI: 10.1111/j.1423-0410.1996.tb01295.x